The hormonal-endocrinology check-up is one of the basic tests for women. This is because a significant percentage of female problems is caused by a disorder in hormone production. The test is performed using an ordinary blood sample; however, the difference with women is that tests must be performed on a specific day of their cycle therefore, therefore for the basic hormonal check-up the blood sample must be taken on the 2nd to the 4th day of their menstrual cycle.
In this context, the hormones checked are FSH, LH, oestradiol, progesterone, prolactin, testosterone, Anti-Müllerian hormone (AMH), androgen-binding globulin, as well as thyroid hormones, as they can affect ovarian function.
These hormones provide us with very important information and guide us. If FSH is found to be very high, this indicates that the ovaries do not produce ova often, while, if the Anti-Müllerian hormone (AMH) produced by ovarian follicles is low, this means not many ovarian follicles are present. With these two important indicators, we can obtain a picture regarding ovum production capacity. Additionally, LH and oestradiol also help us for this purpose. Lastly, based on thyroid hormones we can ascertain if there is damage affecting ovarian function, and, recently, vitamin D3 has been added, as there is evidence supporting that it may affect ovarian function.
It is obligatory in Greece that one of the two parents be tested for thalassemia and this is usually done through haemoglobin electrophoresis. If the woman is found to be a carrier, then a full test must be run on her as well as the man, because in case of thalassemia, as well as sickle cell anaemia, if both are carriers, there is a 25% probability that the child will present the disease. Therefore, prospective parents need to know relevant facts in order for the right genetic consultation to be carried out. At present there is the possibility for pre-implantation genetic diagnosis of these diseases in foetuses, so as to avoid the illness.
Blood samples for general blood tests, blood type, prenatal check tests (toxoplasmosis, cytomegalovirus, rubella) and tests for transmitted diseases, such as Hepatitis A, B, C, HIV (I, II) and syphilis.
Mandatory tests performed in accordance to Law 3305/05 are carried out by taking a blood sample and checking for antibodies against Hepatitis A, B, C, HIV (I, II) and syphilis, before any attempted at assisted reproduction is made.