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The use of molecular biomarkers in minimally invasive sampling opens a promising perspective for the early detection of endometrial cancer. This is the conclusion reached by the members of Screenwide research group, formed by researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO-Hospitalet).

Infection with high-risk strains of the human papillomavirus (HPV), which have been linked to cancer, might increase the risk of heart and blood vessel or cardiovascular disease, especially among women with obesity or other cardiovascular risk factors, according to new research in Circulation Research, an American Heart Association journal.

An interview with Professor Attila Lorincz from Queen Mary University of London (QMUL), discussing the development of a new cervical cancer test that is able to identify cervical cancer and pre-cancer in 100% cases.

How do we currently screen for cervical cancer in the UK?

The main method of cervical cancer screening is the Pap cytology (smear) test, however, we are now slowly transitioning to HPV screening. The cytology test is gradually being replaced and transitioned to a follow-up, or triage test.

 

Compared with non-drinkers, men who consumed at least seven drinks per week during adolescence (ages 15-19) had three times the odds of being diagnosed with clinically significant prostate cancer.

Background: "The prostate is an organ that grows rapidly during puberty, so it's potentially more susceptible to carcinogenic exposure during the adolescent years," said Allott. "For this reason, we wanted to investigate if heavy alcohol consumption in early life was associated with the aggressiveness of prostate cancer later."

Yale Cancer Center (YCC) scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus (HPV) infects cells. Their findings, published online today in the journal Cell, may eventually help to broaden the scope of defenses against HPV and provide valuable clues for delivering drugs into cells.

HPV is a family of killers. Although there are effective vaccines against these viruses, they still cause about 5% of cancer deaths worldwide, including more than 250,000 women who die of cervical cancer each year.

The UK government has announced that boys in England aged 12 to 13 years are to be vaccinated against human papillomavirus, or HPV. This injection would protect them against HPV infection. HPV infection has been linked to cervical cancer in women and oral, penile, throat and anal cancer among men.

 

Human papillomavirus (HPV) is a DNA virus from the papillomavirus family. 3D illustration. Image Credit: Tatiana Shepeleva / Shutterstock

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology.

The University of New Mexico Comprehensive Cancer Center has joined the other 69 cancer centers designated by the National Cancer Institute to issue a statement urging increased vaccination for human papillomavirus.

Nearly 80 million Americans, or one in four people in the United States, are infected with HPV. Of those, more than 31,000 will be diagnosed with an HPV-related cancer this year. The HPV vaccine has been shown to prevent infections, but vaccination rates in the U.S. remain low.

Calling human papillomavirus-related cancers a significant public health problem, the directors of the 70 National Cancer Institute-designated cancer centers, including UNC Lineberger Comprehensive Cancer Center, have issued a joint statement endorsing gender-neutral HPV vaccination and evidence-based cancer screening.

Bottom Line: Parents of adolescents believed that the potential to prevent certain types of cancer is the best reason for their children to receive the human papillomavirus (HPV) vaccine, whereas other reasons health care providers often give were far less persuasive.

Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

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