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Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how "smart" diagnostic-imaging machines identify cancers--and uncovering clues outside the tumor to tell whether a patient will respond well to chemotherapy.

A remarkable recent increase in the diagnosis of vocal-cord cancer in young adults appears to be the result of infection with strains of human papilloma virus (HPV) that also cause cervical cancer and other malignancies. Investigators from Massachusetts General Hospital (MGH) describe finding HPV infection in all tested samples of vocal-cord cancer from 10 patients diagnosed at age 30 or under, most of whom were non-smokers.

A study conducted by researchers at Washington University School of Medicine suggests that it may be possible to use an eye test to screen people for their risk of developing Alzheimer’s disease.

Using a non-invasive eye exam, the researchers detected signs of Alzheimer’s in older people before they had developed any symptoms of the disease.

This technique has great potential to become a screening tool that helps decide who should undergo more expensive and invasive testing for Alzheimer's disease prior to the appearance of clinical symptoms."

You know that warm feeling you get when you see lots of likes from a Facebook or Instagram post? That's the reward system of your brain lighting up like fireflies on a dark summer night.

It's the same system activated in the brains of drug addicts.

By examining the cornea of the eye with a special microscope it may be possible within ten minutes to diagnose if a person with type 2 diabetes has nerve damage. This according to a study among diabetics in Skellefteå, north Sweden.

"Although there is currently no cure, it's always an advantage to detect changes in the nerves early. Therefore, it's valuable to find a fast and safe diagnostic method," says Professor Olov Rolandsson, at the Department of Public Health and Clinical Medicine, Family Medicine, at Umeå University, who was responsible for the study.

Considered a safe and highly effective contraception method, intrauterine devices (IUDs) may also be quietly offering protection against the third-most common cancer in women worldwide. A new study from the Keck School of Medicine of USC has found that IUD use is associated with a dramatic decrease in the incidence of cervical cancer.

An interview with David West, CEO and Hunter Jackson, CSO, Proscia, conducted by April Cashin-Garbutt, MA (Cantab)

How has the digitization of pathology slides impacted cancer diagnostics?

David: It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology.

High risk, potentially cancer causing human papillomavirus infections are common among women in Papua New Guinea. But self sampling with vaginal swabs may provide materials that screen as accurately as the more labor-intensive approach using cervical samples obtained by clinicians. This finding is critical to developing same day screening and treatment, which is key to ensuring that women with precancerous lesions are treated in this largely unconnected (electronically) country, and in others like it.

Biopsy involves the surgical removal of a tissue specimen for histopathologic evaluation. Most intraocular tumors are reliably diagnosed based on the clinical evaluation or with noninvasive diagnostic techniques. However, accurately diagnosing a small percentage of tumors can be challenging. A tissue biopsy is thus needed to establish a definitive diagnosis and plan the requisite treatment. From fine-needle aspiration biopsy (FNAB) to surgical excision, all tissue collection techniques have been studied in the literature. Each technique has its indications and limitations.

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