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Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

More than a million people worldwide are diagnosed with colon cancer every year. Although many of these cases are spontaneous, chronic inflammation is one of the main causes underlying the development of this disease.

UT Southwestern researchers have identified a major mechanism by which obesity causes type 2 diabetes, which is a common complication of being overweight that afflicts more than 30 million Americans and over 400 million people worldwide.

Body fat distribution in the trunk is more important than body weight when it comes to cancer risk in postmenopausal women, according to a study presented at the ESMO 2017 Congress in Madrid.

The findings put a new spin on weight management priorities for women in this this age-group, who are prone to abdominal weight gain, said study investigator Line Mærsk Staunstrup, MSc, a PhD student with Nordic Bioscience and ProScion, in Herlev, Denmark.

For several years, medical researchers, doctors and dieticians have known that a low carbohydrate diet and plentiful fat can prevent a range of lifestyle and age-related diseases and thus promote healthy aging. But researchers from around the world have not been able to explain why this is the case. They have just been reasonably certain that the energy metabolism and its chemical intermediates (metabolites) play a central role.

Results of a study carried out in Brazil showed a strong association between vitamin D deficiency and metabolic syndrome in postmenopausal women. The Metabolic syndrome (MetS), described as a cluster of conditions that heighten the risk of heart disease, stroke and diabetes, is estimated to affect approximately 50% of the female population above the age of 50 in the United States.

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