The prevalence of anal high-grade squamous intraepithelial lesions (HSIL), which precede anal cancer, is much higher in women living with HIV than previously reported, a multi-site, national study involving hundreds of patients has found. Conducted by researchers from the AIDS Malignancy Consortium, a National Cancer Institute-supported clinical trials group, the results call for new strategies to be developed for wider screening of women living with HIV, who have disproportionally higher rates of anal cancer compared to the general population of women.
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A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial.
The shot, a therapeutic vaccine, injects a specific protein that triggers an immune system response to attack high-risk HPV types that cause nearly all cervical cancer precursors, known as cervical intraepithelial neoplasia, or CIN.
A new study reports that a type of cervical cancer that is less amenable to Pap testing is increasing in several subpopulations of women, pointing to the growing importance of human papillomavirus (HPV) testing and vaccination. The study appears early online in Preventive Medicine.
A record number of homeless people — 918 last year alone — are dying across Los Angeles County, on bus benches, hillsides, railroad tracks and sidewalks.
Deaths have jumped 76% in the past five years, outpacing the growth of the homeless population, according to a KHN analysis of the coroner's data.
Whilst it is widely accepted that smoking causes lung cancer, a lesser known fact is that ~6000 non-smokers die of lung cancer every year in the UK. One potential reason for this number is air pollution, according to a recent report by Public Health England (PHE). As these patients do not smoke, they are often overlooked when it comes to diagnosing lung cancer, and diagnosed late, with poor outcomes.
Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.
Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how "smart" diagnostic-imaging machines identify cancers--and uncovering clues outside the tumor to tell whether a patient will respond well to chemotherapy.
Scientists at the UNC School of Medicine have revealed that the reason we eat more than we need to may be caused by cellular communication originating in the emotion-processing center of the brain. The research was published in the journal Neuron yesterday.
New findings about a fatal form of blood cancer could aid the development of new drugs with significantly less harmful side effects than existing chemotherapy.
The discovery could lead to novel treatments that efficiently eliminate blood cancer cells in acute myeloid leukaemia (AML), without harming healthy blood cells.
Researchers have discovered how a protein in the body plays a key role in AML - an aggressive cancer of white blood cells with very poor survival rates.
Most people think of optimism as a good thing - a positive outlook in challenging circumstances. But in reality, it's a psychological state that can be "contagious" in a bad way. A new study, published in the journal Psycho-Oncology, details how a seriously ill patient's optimism can impact a clinician's survival prognosis in palliative care conversations.